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AACR-NCI-EORTC 2019 - AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Oct 26 - Oct 30, 2019 | BostonMAUS

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Showing 48 abstracts linked to Trials

Anti-angiogenic activity of the CXCR4 antagonist balixafortide

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A phase 1/2a, open-label, dose-escalation study of EC-18 in patients with metastatic breast cancer for the prevention of chemotherapy-induced neutropenia

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Preliminary results of ASTX660, a novel non-peptidomimetic cIAP1/2 and XIAP antagonist, in 107 patients with solid tumors or lymphoma

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Using prebaseline and on-treatment tumor assessments to compare time to tumor size progression of hormonal therapy + sapanisertib vs an extrapolated hormonal therapy alone from a single-arm phase 2 study

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Correlation of homologous recombination deficiency (HRD) status by BROCA-HR sequencing with response to combination cediranib and olaparib in relapsed ovarian cancer

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FIGHT-207: Phase 2 study of pemigatinib in patients with previously treated, locally advanced/metastatic or unresectable solid tumor malignancies harboring activating fibroblast growth factor receptor (FGFR) gene alterations

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FIGHT-101: A phase 1/2 study of pemigatinib, a highly selective fibroblast growth factor receptor (FGFR) inhibitor, as monotherapy and as combination therapy in patients with advanced malignancies

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A phase 1, first-in-human, dose-escalation study of ADG106, a fully human anti-CD137 agonistic antibody, in subjects with advanced or metastatic solid tumors and/or relapsed/refractory non-Hodgkin lymphoma

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Second-line treatment of recurrent/refractory (R/R) glioblastoma multiforme (GBM, WHO grade 4) and anaplastic astrocytoma (AA, WHO grade 3) with a first-in-class anti-TGFβ2 RNA therapeutic administered intratumorally via convection-enhanced delivery

Phase Ib study of a novel MDM2 inhibitor APG-115, in combination with pembrolizumab in patients with metastatic solid tumors in U.S.

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Novel anti-EGFR antibody-drug conjugate AVID100: A phase 2a trial in patients with EGFR-overexpressing advanced solid tumors

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Identification of resistance mechanisms to FGFR4 targeted therapy in hepatocellular carcinoma

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Safety and efficacy of ZW25, a HER2‑targeted bispecific antibody, in combination with chemotherapy in patients with locally advanced and/or metastatic HER2-expressing gastroesophageal cancer

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